Migraine is a common problem experienced by a large segment of the population. The presence of migraine can mimic or accompany the presentation of common otolaryngologic complaints such as sinus pain, headache, otalgia, vertigo, aural fullness, and fluctuating hearing loss. Many patients experience migraine in ways that exacerbate symptoms from their otolaryngologic problems or suffer migraine symptoms triggered by their otolaryngologic problems and will benefit from migraine therapy. Unfortunately, only patients with severe or debilitating classic migraine tend to receive significant attention from their primary physicians or from neurologists who treat the majority of migraineurs in this country. This session seeks to fill a gap in otolaryngology training by acquainting the practicing Otolaryngologist with an update on the pathophysiology of migraine and will present sound treatment strategies for patients who have migraine headache or atypical manifestations of migraine. Learning Objectives: 1.Identify the difference between migraine syndrome and migraine headache. 2. Analyze recent discoveries regarding the role of the fifth cranial nerve and electrical disturbances in the brain and brainstem in the pathophysiology of migraine symptoms. 3. Identify sound treatment strategies to decrease migraine symptoms and migraine headache. Faculty: John P. Carey, MD(Research funding: Otonomy), Michael T. Teixido, MD(Nothing to disclose).