Patients who have lost their smell and taste are desperate for help, but unfortunately every year millions are told by their physicians that there is nothing that we can do to help them. This is certainly no longer the case. This panel presentation will provide the general otolaryngologist with practical tips on how to offer not only hope, but real therapeutic options to their patients with this devastating problem. Learn the benefits current treatment options provide and which once-popular suggested remedies have been disproven and find out what translational studies are underway to bring the latest cutting-edge research to your patients. Learning Objectives: 1.Explain the latest proven treatment options to patients with olfactory loss. 2. Understand which treatment options have been disproven to help patients with olfactory loss. 3. Analyze the latest research and direct patients with olfactory loss to sites where clinical translational studies are underway. Faculty: Zara M. Patel, MD(Honoraria: Intersect ENT; Consulting Fees: Medtronic; Patara Pharma), Eric H. Holbrook, MD(Expert Witness: Margol & Margol; Leadership Role: ARS Consulting Fees: 480 Biomedical), Justin H. Turner, MD, PhD(Research funding: American Rhinologic Society; NIH; Consulting Fees: Intersect ENT), Bradley J. Goldstein, MD, PhD(Nothing to disclose), Greg E. Davis, MD, MPH(Research funding: Synedgen; Consulting Fees: Medtronic; Intersect).