How can we most effectively evaluate patients with dizziness within the confines of modern practice? During this panel presentation, jointly sponsored by the Otology Neurotology Education Committee and Equilibrium Committee, experts in vestibular diagnosis will discuss how to integrate best evidence with clinical experience to efficiently formulate a differential diagnosis for any patient with dizziness. By working through illustrative cases, we will present the key questions – focused on timing, triggers, and associated symptoms – that elicit the pertinent history and minimize vague reporting. We will also review the highest yield physical exam elements that warrant incorporation into daily practice using video clips to illustrate technical pearls and findings. With this diagnostic framework established, we will guide clinicians in determining what tests to order, if any, by defining the specific questions that can and cannot be answered with the current array of audio-vestibular tests, imaging, and other physiologic investigations. We will incorporate audience response to maximize engagement at various stages of clinical decision making. We aim to provide an approach that clinicians can readily implement to make correct diagnoses in a timely fashion, thus expediting initiation of therapy and improving patient outcomes.