One of the main challenges to define the best OSA treatment path hinges on the accurate definition of “successful result”, as some of the commonly used sleep study metrics have little to no correlation with clinically meaningful outcomes and offer limited perspective on the strategy procedure for each individual. In addition, decisions around treatment selection and in the case of surgery, perioperative routines are based on less than-ideal evidence to support or refute its usefulness. To target this issue, our team gathered multidisciplinary talent with medical, business, computer science, and statistics expertise aiming to collect, refine and analyze large volumes of data presented by claims databases, electronic medical records (EMRs) to produce Real World Evidence, and at the session, we will review published data that will assist in defining clinically relevant deliverables and peri-operative efficient routines.