Unilateral vocal fold paralysis (UVFP) is a common voice disorder with husky voice and aspiration during swallowing that significantly impair the patient’s quality of life. A prompt symptoms relief is a universal strong willing of all suffered patients and office-based injection laryngoplasty has gain popularity in the modern era. Because the medical environments are variable from institution to institution and patients’ demands are usually variable, various treatment methods with different combinations of approaches and injection fillers have been developed in the injection laryngoplasty category. In this program, the panelists plan to introduce various office-based injection laryngoplasty techniques ranged from commonly used flexible laryngoscopy guidance injection to innovative laryngeal electromyography guidance injection; from autologous fat injection to different commercially available fillers. The first panelist will introduce the unique technique of trans-thyrohyoid structural injection with multilayered/multipoint fat injection under flexible digital laryngoscopy guidance to achieve even medialization of paralyzed vocal fold. The long-term results of 77 patients will be presented. The second panelist will introduce another innovative Laryngeal Electromyography Guided Hyaluronic Acid Injection Laryngoplasty which provides patients additional prognostic information of UVFP. The long-term results of hundreds of patients over 10 years will be presented to prove the advantage of this novel approach. The last panelist will share his experience in flexible laryngoscopy guided injection in patients with various etiologies of UVFP. The different treatment results in different etiologies will be discussed. In summary, the audience could learn new knowledge about different injection approaches, different injection fillers, the innovative way to obtain prognosis prediction information, and the treatment results of office-based injection laryngoplasty from 3 medical centers in Taiwan.