Autoimmune diseases compromise a heterogeneous group of connective tissue disorders that can manifest in the larynx and trachea. Early diagnosis and proper management, both surgical and medical, are keys to preserving laryngeal function. This course will teach learners to identify the laryngeal and airway manifestations of a variety of rheumatologic conditions (including rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome, relapsing polychondritis, sarcoid, and granulomatosis with polyangiitis) and proper next steps in workup and management. Both medical and surgical management will be reviewed. By the end of the course, the participant will be able to recognize laryngeal manifestations of autoimmune disorders, describe appropriate work-up, and identify management strategies.