Several key relationships can be developed to facilitate career advancement. These relationships can be either mentorship or sponsorship type affiliations. Mentorship involves transfer of knowledge and guidance from an experienced person to a less experienced person or novice. Mentorship relationships often discuss lived experience to impart wisdom. Different types of mentorship relationships are recognized including structured vs informal, short term vs long term and active vs passive; the benefits of each type of mentoring will be discussed. Sponsorship utilizes the resources of the experienced partner to actively promote and advocate directly for their junior partner. Sponsors utilize their social and professional networks to “open doors” for the sponsored partner. Some professional relationships involve aspects of both sponsorship and mentorship. Mentorship and sponsorship are important features for all physicians and can be formative for those just entering practice, private and academic alike. Key features of successful mentorship and sponsorship partnerships will be discussed. Panelists include a senior academician, a seasoned private practitioner, and a junior faculty member. Each panelist will discuss their experiences as mentors, mentees, and sponsors/sponsored partners. The difference between academic and private practice relationships will be explored. Audience polling will be utilized to assess the broader experiences of the group. Attendees will learn 3 key behaviors which they can apply to their own mentorship and sponsorship relationships to facilitate their own career advancement.