Drug induced sleep endoscopy (DISE) was initially introduced in Europe in the early 2000s to evaluate sites of upper airway obstruction in adult patients with OSA. DISE is now commonly performed as part of the evaluation for adults being considered for sleep surgery. There is a widely utilized standardized scoring system, and data is also emerging regarding improved outcomes in adult patients that have undergone DISE-directed sleep surgery. Only in more recent years has DISE been performed with increasing frequency in children with OSA. High-quality, prospective studies on pediatric DISE are lacking. Thus, there are significant variations in practice among providers performing this procedure. For example, the optimal sedation protocol for children undergoing DISE is still debated. To provide guidance for providers performing pediatric DISE and with the goal of quality improvement, the American Academy of Otolaryngology Head and Neck Surgery Foundation convened a group of pediatric OSA expert panelists to develop a clinical consensus statement on this topic. This panel discussion will highlight the main findings of the recently published consensus statement. Panelists, which will be include leadership from the consensus statement, will use a case-based approach to address the numerous controversies surrounding pediatric DISE such as the lack of a widely accepted scoring system and variations in DISE technique. We will also discuss consensus statements related to indications for pediatric DISE including the role of this procedure in children who have yet to undergo adenotonsillectomy. A brief review of the most recent, pertinent DISE literature will be included along with expert commentary. The panelists will offer practical suggestions on how to incorporate consensus statement recommendations into their practice.