Electronic cigarette (e-cigarette) vaping was deemed a public health “epidemic” in 2018, and the prevalence of vaping has continued to increase among adolescents and young individuals. Tobacco regulation was one of four key legislative priorities for AAO-HNS in recent years, and data continue to demonstrate harm to respiratory epithelial cells by e-cigarette vapor. Since Otolaryngologists see patients for many ‘primary care’ complaints, we are often at the healthcare portal of entry for many young individuals whom we may be able to counsel about the adverse effects of vaping. Additionally, potential long-term side effects of vaping are unknown and may lay within the realm of Otolaryngologic care. This panel will review the magnitude of e-cigarette use in the United States, and the emerging data on associated adverse effects. This panel will empower Otolaryngologists in both private and academic settings to educate patients about presently known adverse effects of vaping and promote vaping cessation alongside pediatricians and addiction specialists. This expert panel will include lead NIH-funded vaping researchers from one of 14 Centers for Tobacco Regulatory Science and Lung Health (TCORS) in the United States who will educate Otolaryngologists about known deleterious effects of vaping, and how vaping prevention and cessation can be addressed in clinical settings.